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For years, view­ers have watched TLC’s My 600-Lb Life, wit­ness­ing mor­bid­ly obese patients com­plete­ly trans­form their bod­ies and lives. The patients pro­filed on the show all start out hun­dreds of pounds over­weight, with the dev­as­tat­ing health and emo­tion­al prob­lems that come with that. From being unable to walk and do every­day tasks to being home­bound, the patients suf­fer the most extreme phys­i­cal and emo­tion­al con­se­quences of obe­si­ty.

But all of them have some­thing in com­mon — hope and a desire to change. In comes the show’s cen­tral fig­ure, Dr. Younan Nowzaradan. “Dr. Now,” as his patients call him, is a bariatric sur­geon who per­forms weight loss surg­eries on his patients and coach­es them along the road to a healthy weight. Over the sea­sons, dozens of peo­ple have made a com­plete turn­around, going from bare­ly mobile to active and fit. And while most patients on the show lose weight, there are some that real­ly stand out.

Check out some of the most stun­ning weight-loss suc­cess sto­ries to ever be chron­i­cled on My 600-Lb Life.

Amber Rach­di

Amber Rachdi’s trans­for­ma­tion is one of the most jaw-drop­ping. When she first appeared on the show at age 23, sheweighed 657 pounds and said she felt like a “nasty, yucky mon­ster.” Her legs car­ried a great deal of her weight, and, as a result, she said she could­n’t stand for more than 30 min­utes at a time. After los­ing 20 pounds in order to qual­i­fy for gas­tric bypass surgery with Dr. Now, she under­went the pro­ce­dure and end­ed up get­ting down to 377 pounds with­in a year!

But she did­n’t stop there, she ulti­mate­ly lost over 400 pounds and kept it off, pro­fil­ing her jour­ney with glam­orous pin­up-style self­ies on Face­book and Insta­gram. She explained on Insta­gram, “I spent a long time not lik­ing me, so I’m doc­u­ment­ing moments I feel pret­ty.”

Rach­di, who con­fessed on her episode ofMy 600-Lb Life that her weight pre­vent­ed her from being inti­mate with her then-boyfriend, now has a lot to cel­e­brate when it comes to her per­son­al life. She got engagedin 2016 and has since tied the knot.

Brit­tani Fulfer

Brit­tani Fulfer­’s sto­ry is noth­ing short of remark­able. She start­ed out weigh­ing 605 pounds at only 5 feet, 1 inch tall. She was so moti­vat­ed to change that she and her hus­band, Bill, moved from Ore­gon to Texas in order to be near Dr. Now’s office, where she under­went weight loss surgery.

Accord­ing to Wom­en’s Health mag­a­zine, she lost almost 400 pounds and dropped down to 222. She explained her rea­son for hav­ing surgery to the mag, “I felt I had more to offer myself, friends, and fam­i­ly than just hav­ing them help take care of me. I was too young to feel so old.”

She said she is cher­ish­ing every moment of her new life, and she told Wom­en’s Health, “I knew when I start­ed this jour­ney that my life was going to get bet­ter. But, I had no idea that my life was going to be this amaz­ing! My weight was my prison. Now I am free, and I can do what­ev­er I want when­ev­er I want.

Angel Par­rish

Angel Par­rish weighed 570 pounds when she first appeared on the show, rid­ing in a wheel­chair and rely­ing on her boyfriend, Don­nie, for every­day needs. She said that her eat­ing habits had been trig­gered by the trau­ma of plac­ing a baby for adop­tion at age 14, and the sit­u­a­tion got worse when she lat­er expe­ri­enced post­par­tum depres­sion after giv­ing birth to a son with Don­nie.

Don­nie went so far as to say that she “just stopped liv­ing” after their son Andrew was born. He threat­ened that if she did­n’t get help, he’d have to leave her and take Andrew with him.

Par­rish rebound­ed in a big way by los­ing over 150 pounds through diet changes, and then under­go­ing weight-loss surgery with Dr. Now. She adopt­ed a fit­ness rou­tine and ulti­mate­ly dropped over 300 pounds. After los­ing the weight, she reflect­ed, “It’s been a long time since I could look at myself and see some­one that I thought was beau­ti­ful.”

After slim­ming down, she was able to be a more active par­ent, and said, “I wake up and it’s not to eat — it’s to get Andrew ready for school!”

Melis­sa D. Mor­ris

Melis­sa D. Mor­ris was one of the first peo­ple to be pro­filed on the show, and she start­ed her weight loss jour­ney over a decade ago. She began her jour­ney at 653 pounds and was forced to ride around in a scoot­er to car­ry out basic tasks like gro­cery shop­ping.

After under­go­ing weight loss surgery, she dropped down to a stun­ning 137 pounds! And to make things even sweet­er, after 12 years of try­ing to get preg­nant, she final­ly became a mom, wel­com­ing three chil­dren over the years. She strug­gled with her weight after her preg­nan­cies, but still weighs sig­nif­i­cant­ly less than she did when she began. She told TLC in 2017, “I weigh myself every sin­gle day. I am so fear­ful of gain­ing all my weight back, espe­cial­ly because it was so easy for me to gain [weight] while preg­nant.”

She also shared some advice for peo­ple who might want to change their lives like she did. “I advise oth­ers that the first step towards a health­i­er life is iden­ti­fy­ing what you’re doing wrong. You must first fig­ure that out because you can­not fix what you don’t acknowl­edge,” she said.

Christi­na Phillips

Christi­na Phillips weighed in at 673 poundsat only 22 years old when she first vis­it­ed Dr. Now, and said that she was so embar­rassed about her weight that she only left the house at 3 a.m. when she was unlike­ly to see many peo­ple.

She told Wom­en’s Health, “Get­ting up and walk­ing just a few feet made me feel like I was going to die. I could­n’t dri­ve, walk far, or go out with friends and fam­i­ly. I was mis­er­able, and I knew I had to do some­thing.”

With the help of Dr. Now, Phillips had weight loss surgery and expe­ri­enced a shock­ingtrans­for­ma­tion — her weight loss end­ed up being so extreme that she actu­al­ly lost too much weight! The doc­tor advised her to gain 15 pounds in order to be at a more healthy weight.

In 2017, she told Wom­en’s Health that she weighed in at 171 pounds and said, “My life has changed so much since the weight loss! I can do things I nev­er imag­ined pos­si­ble… I’ve been able to try indoor sky­div­ing and… I can walk miles with­out get­ting tired.”

Nik­ki Web­ster

Nik­ki Web­ster is one of the most notable suc­cess sto­ries on the show. She orig­i­nal­ly weighed in at 649 pounds, and her weight was affect­ing her career in cos­tume design. Luck­i­ly, she had strong sup­port from her fam­i­ly (her dad lost 40 pounds in sol­i­dar­i­ty) and was able to under­go gas­tric bypass surgery with Dr. Now.

Accord­ing to Peo­ple mag­a­zine, she ulti­mate­ly lost 450 pounds. In 2017, she told the mag, “It’s hard to imag­ine now how I used to live. It’s just become so vast­ly dif­fer­ent. … It has been the hard­est two years of my life, but it’s been the most vic­to­ri­ous and excit­ing.”

She explained how she stays fit, tellingPeo­ple, “I do a lot of walk­ing, that’s my favorite thing to do. I’ll walk at least 2 to 3 miles a day or I try to. I’ll also try to do weight train­ing and that kind of thing. I go to the gym every now and then and do those sorts of things.”

In 2018, Nik­ki revealed on Face­book that she’d got­ten mar­ried, writ­ing, “I kind of got mar­ried. He’s the absolute best, and I hon­est­ly could­n’t be more happy…It’s been a busy few months.”

Paula Jones

When Paula Jones decid­ed to lose weight, she had a pow­er­ful and trag­ic moti­va­tion — her hus­band had died from weight-relat­ed com­pli­ca­tions from weigh­ing over 600 pounds. A year after he passed away, Jones her­self weighed 542 pounds and wor­ried that she too would suf­fer a life-threat­en­ing com­pli­ca­tion from obe­si­ty, leav­ing her four chil­dren on their own.

She decid­ed that it was time to change and paid a vis­it to Dr. Now, but she was stunned when she set foot on the scale and saw her weight. “I’m huge. I look like a mon­ster,” she said sad­ly.

Jones fol­lowed through with her com­mit­ment to trim down, mov­ing her fam­i­ly from Geor­gia to Texas in order to have surgery. Accord­ing to Wom­an’s World, it paid off and she expe­ri­enced amaz­ing results, ulti­mate­ly los­ing 400 pounds! The mag report­ed that her rela­tion­ship with her kids has improved, with Jones say­ing, “I can be more active with them. I’ve learned how to be emo­tion­al­ly healthy as well as phys­i­cal­ly healthy.”

Chuck Turn­er

Chuck Turn­er weighed in at 693 pounds when he first appeared on the show. He said that he start­ed gain­ing weight years ear­li­er after his first wife was mur­dered. He even­tu­al­ly mar­ried his sec­ond wife Nis­sa and they adopt­ed a son togeth­er, but his mar­riage became strained when his obe­si­ty pre­vent­ed him from help­ing her with any­thing around the house.

Accord­ing to In Touch Week­ly, his sit­u­a­tion had grown even more com­pli­cat­ed because a 40-pound growth called a lym­phede­ma had devel­oped on his leg, hin­der­ing his move­ments even fur­ther. He told TLC pro­duc­ers, “I’d rather be a dead man than have to live like this for the rest of my life.”

Luck­i­ly, he was able to have weight-loss surgery with Dr. Now, and he end­ed up los­ing 433 pounds! Unfor­tu­nate­ly, he and Nis­sa even­tu­al­ly split up, but, accord­ing to In Touch, he said in a reunion spe­cial that he was look­ing for love again.

Zsalynn Whit­worth

Zsalynn Whit­worth’s sto­ry is remark­able due to all that she had to over­come to lose weight. On her episode of My 600-Lb Life, she described join­ing a fat-accep­tance orga­ni­za­tion and fly­ing around the world to par­ty with men who enjoyed the com­pa­ny of large women.

Unfor­tu­nate­ly, by the time her weight had crept up to over 600 pounds, it was­n’t so fun any­more. Now a moth­er to a young daugh­ter, she found it hard to move around and spent up to 8 hours per day watch­ing TV. She said she now “hat­ed being this size” so she embarked on a jour­ney with Dr. Now, and just a year after her weight loss surgery, she had lost 247 pounds.

But unfor­tu­nate­ly, accord­ing to the Dai­ly Mail, her hus­band Gareth liked larg­er ladies and was­n’t a fan of her slim­mer frame. He encour­aged her to eat unhealthy foods so that she could gain weight. She had to decide whether to stay with some­one who was active­ly try­ing to sab­o­tage her weight loss suc­cess, or get a divorce, and she report­ed­ly end­ed up opt­ing for the lat­ter.

Don­ald Shel­ton

Don­ald Shel­ton’s weight loss jour­ney was a bit of a bumpy road with lots of twists and turns. When view­ers were first intro­duced to him, he weighed 675 pounds and his weight made it hard to move around, caus­ing him to ride in a wheel­chair. His immo­bil­i­ty led to severe bouts of depres­sion.

After weight loss surgery with Dr. Now, he was able to lose almost 400 pounds, but, accord­ing to In Touch Week­ly, he was unfor­tu­nate­ly diag­nosed with Guil­lain-Barre syn­drome, which affect­ed his abil­i­ty to walk and required him to be wheel­chair-bound again. Unfor­tu­nate­ly, after this dev­as­tat­ing set­back, he report­ed­ly gained back 200 pounds.

But, like the oth­er high­ly moti­vat­ed stars ofMy 600-Lb Life, Shel­ton did­n’t give up. Accord­ing to In Touch, he was ulti­mate­ly able to drop some of the weight he put on, and he looked trim and hap­py in lat­er social media posts.

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